The website offers odds on all top-tier eSports events and offers customers the option of betting in real-money or the Bitcoin virtual currency.
Players will be able to place bets on eSports events and tournaments such as the League of Legends World Championship, the Evolution Championship Series and the Battle.net World Championship Series.
Customers will also have access to a live casino, a Bitcoin dice game and a lottery that features automatic draws every few minutes.
In addition, VitalBet plans to roll out an full online sportsbook in due course.
David Blatt, sportsbook manager at VitalBet, said: “We offer players an unmatched betting experience through a variety of promotional offers, as well as Progressive and Mystery Jackpots, full and partial bet cashouts, multi-level VIP player loyalty program, and combo bet bonuses.
“We are both online and on your mobile device with a unique and beautiful mobile betting interface.”